风痛宁丸治疗类风湿关节炎的临床疗效观察

Clinical effect observation of Fengtongning pills in the treatment of rheumatoid arthritis

目的探讨风痛宁丸治疗类风湿关节炎的临床疗效。方法选取2010年4月-2013年7月门诊部收治的类风湿关节炎患者106例,随机分为观察组和对照组各53例。观察组予风痛宁丸治疗,对照组予西医治疗,比较2组治疗疗效。结果观察组总有效率为88.68%明显高于对照组的75.47%,差异有统计学意义(P<0.05)。2组治疗后关节功能均优于治疗前,观察组双手握力、晨僵指数、功能指数、肿胀指数及疼痛指数改善情况均优于对照组,差异有统计学意义(P<0.05);20m步行时间比较差异无统计学意义(P>0.05)。观察组不良反应发生率明显低于对照组,差异有统计学意义(P<0.05)。结论风痛宁丸治疗类风湿关节炎临床效果良好,关节功能改善明显,不良反应发生率低,值得临床推广应用。

Objective To explore the clinical curative effect of Fengtongning pills in the treatment of rheumatoid arthritis. Methods 106 cases of patients with rheumatoid arthritis in the outpatient department from April 2010 to July 2013 were divided into the observation group and control group, each of 53 cases. The observation group received Fengtongning pill for treatment,while the control group took the western medicine treatment. The effect of 2 groups was compared. Results The total effective rate of observation group was 88.68% ,which was higher than 75.47% of the control group,the difference was statistically significant （ P 〈 0. 05 ）. After treatment, the joint function of 2 groups was better than before treatment ; The hands grip strength,stiffness index ,function index, swelling index and pain index of observation group were better than those of the control group,the differences were statistically significant（P 〈 0.05）. There was no significant difference of 20m walking time between 2 groups （ P 〉 0.05）. In addition ,the incidence of adverse reaction of the observation group was lower than that of the control group, the difference was statistically significant （ P 〈 0.05 ）. Conclusion Fengtongning pills in the treatment of rheumatoid arthritis with good clinical efficacy, with lower incidence of adverse reactions, which is worthy of promotion.