肠易激综合征中医证候与焦虑、抑郁情绪的关系研究

The Research on the Relationship Between TCM Syndrome of Irritable Bowel Syndrome and Anxiety and Depression

目的探讨肠易激综合征(IBS)中医辨证分型与患者焦虑、抑郁情绪的关系,为IBS的辨证论证提供客观化依据。方法搜集114例IBS患者的四诊信息并辨证分型,采用焦虑自评量表(SAS)和抑郁自评量表(SDS)评价患者的焦虑、抑郁状况,行简单对应分析。结果 IBS的不同中医证型所表现的焦虑、抑郁心理存在差异。肝郁气滞证的点集合与焦虑、抑郁点集合的距离最近,肝郁脾虚证的点集合与焦虑并抑郁点集合的距离最近,脾胃虚弱证、脾虚湿盛证和脾肾阳虚证的点集合与无焦虑抑郁点集合的距离最近。结论 IBS的肝郁气滞证和肝郁脾虚证患者具有明显的焦虑抑郁情绪,这对IBS中医辨证分型有一定提示作用。

Objective To investigate the relationship between TCM syndrome differentiation of irritable bowel syndrome（IBS）and patients＇ anxiety and depression, and provide objective evidence for the dialectical argument on IBS. Methods The information of 114 cases of patients with IBS was collected and their TCM syndrome differenti- ation was obtained by the four methods of diagnosis. The anxiety and depression condition of the patients was eval- uated by using self-rating anxiety scale（SAS）and self-rating depression scale（SDS）. The simple correspondence a- nalysis to these two sets of data was performed. Results There were differences between the different TCM syn- drome types of IBS in anxiety and depression. The distance between multipoint of the liver-depression and Qi-stag- nation syndrome and the anxiety and depression is the nearest. The distance between multipoint of the liver-depres- sion and spleen-deficiency syndrome and the anxiety with depression is the nearest. Furthermore, the distance be- tween multipoint of the weakness of spleen and stomach syndrome,damp abundance due to splenic asthenia and in- sufficiency of both the spleen and the kidney and the non-anxiety and non-depression is the nearest. Conclusion It suggests that IBS patients with the liver-depression and Qi-stagnation syndrome or the liver-depression and spleen- deficiency syndrome have obvious anxiety and depression which may have a role in prompting TCM syndrome dif-ferentiation.