肾纤维化功能性MRI的研究进展

Progresses of functional magnetic resonance imaging in renal fibrosis

肾纤维化可导致肾功能衰竭,是终末期慢性肾病常见的结局,也是肾移植失败的最常见原因。因此,肾纤维化的程度与患者预后密切相关。临床上检测肾纤维化造成肾功能不全的方法有很多,但是目前缺乏一种活体无创性动态监测肾纤维化的可靠手段。f MRI在检测肾功能、评估肾纤维化程度方面近来越来越受到重视。作者回顾和分析了过去几年肾脏的几种f MRI在肾纤维化这一领域的发展。

Renal fibrosis can lead to renal failure, it is a common outcome of end-stage chronic kidney disease, and the most common cause of kidney transplant failure. Therefore, the degree of renal ifbrosis is closely related to the prognosis and patients. Although some methods can inspect renal ifbrosis and renal insufifciency well, none of them can non-invasively detect renal ifbrosis in vivo perfectly. Recently, more and more researches about renal fibrosis and renal insufficiency diagnosis by functional MRI were reported. This paper reviews and analyzes some functional MRI progresses about renal ifbrosis in the past few years.