摘要
目的:观察洁淋通丸治疗泌尿系感染的临床疗效。方法:240例泌尿系感染患者随机平均分为治疗组和对照组。治疗组给予自制中药洁淋通丸,对照组给予银花泌炎灵。治疗后观察两组患者临床疗效、临床症状、血清白介素-6(interleukin-6,IL-6)、肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)水平变化情况。结果:治疗组有效率为96.7%,对照组有效率为95.9%,两组疗效比较,差异无统计学意义(P>0.05)。两组治疗后各种症状均较治疗前明显改善(P<0.01);两组之间比较,差异无统计学意义(P>0.05)。两组均能显著降低血清IL-6、TNF-α水平(P<0.01),且治疗组优于对照组(P<0.01)。结论:洁淋通丸治疗泌尿系感染临床疗效显著,其机制可能是降低血清TNF-α、IL-6水平,抑制炎症反应。
Objective:To observe the clinical curative effect of Jie Lin Tong Pill in the treatment of urinary tract infection.Methods:The patients were randomly divided into the treatment group and the control group of 240 cases of urinary tract infection.The treatment group was given the self-made traditional Chinese medicine Jie Lin Tong Pill,the control group was given Yinhua Miyanling.To observe the clinical efficacy of the two groups,the clinical symptoms,seruminterleukin-6(interleukin-6,IL-6),tumor necrosis factor alpha (tumor necrosis factor-TNF-alpha,alpha)changes.Results:The effective rate of treatment group 96.7%,control group effective rate was 95. 9%,Comparison of the efficacy of the two groups,the difference was not statistically significant (P〉0.05).The two groups after treat-ment the symptoms were significantly improved after treatment (P〈0.01);the comparison between two groups,no significant difference (P〉0.05).The two groups can significantly reduce the blood serum IL-6,TNF-αlevel alpha(P〈0.01),and the treatment group was better than that of the control group (P〈0.01).Conclusion:The clinical effect of Jie Lin Tong Pill treatment of urinary system infection is good,and its mechanism may be through the reduction of serum TNF-α,IL-6 levels,inhibit inflammatory reaction to achieve.
出处
《中医学报》
CAS
2015年第5期745-747,共3页
Acta Chinese Medicine
基金
河南省科技成果转化项目(132201610011)