331例患者中/长链脂肪乳注射液临床用药合理性分析

Analyzation of the rational clinical use of MCT/LCT emulsion injection in 311 patients

目的评价该院中/长链脂肪乳注射液临床使用合理性,为其合理用药提供参考。方法抽取2013年8—12月份该院所有使用中/长链脂肪乳注射液的住院患者的病历,采集相关信息,根据相关标准进行专项点评。结果调查的331例患者中,外科所占比例最大,57.70%;其次为结核科17.82%、呼吸科10.57%、肿瘤科9.67%、急诊科3.63%、内科0.60%。不合理病例比例为34.44%。无适应证用药17.52%,遴选药品不适宜5.74%,用法用量不正确0.00,有配伍禁忌的为3.63%,未监测脂肪廓清能力13.60%。结论从调查结果中发现,中/长链脂肪乳注射液临床应用不合理现象较为普遍,医院需进一步强化药物规范使用。

Objective To evaluate the rational clinical use of MCT/LCT emulsion injection to provide reference for its rational use. Methods Collected relevant information by extracting medical records of all the inpatient who injected with MCT/LCT emulsion from Aug,2013 to Dec,2013,and gave special comments in accordance with the relevant standards.Results Among the 311 cases,patients from the surgery department hold the largest proportion （57.70%）,followed by the tuberculosis department,accounting for 17.82%. The rest are respiratory department which holds 10.57%,oncology department holding 9.67%,emergency department holding 3.63%, and internal medicine holding 0.60%.Unreasonable medical records take 34.44%;no indication of medication use takes 17.52%,in-appropriate selection of drugs takes 5.74%,incorrect dosage takes 0.00,incompatibility takes 3.63%,and unmonitored fat clearance capacity takes 13.60%.Conclusions Based on the survey results,unreasonable use of MCT/LCT emulsion injection in clinical appli-cation is more prevalent,and hospital needs to further strengthen the standardized drug use.