摘要
目的:探讨去氧孕烯炔雌醇预防宫颈子宫内膜异位症的效果,总结临床经验,为今后该类患者的防治工作提供理论依据。方法:选取2011年6月至2013年6月间医院收治的68例行物理手段治疗宫颈糜烂的患者作为样本。将其随机分为两组,对照组34例患者,术后行抗生素治疗;治疗组34例患者在此基础上加以口服去氧孕烯炔雌醇2个月进行治疗。比较两组患者术中出血量、术后宫颈愈合时间、宫颈子宫内膜异位症发生情况。结果:治疗组的患者平均术中出血量为(4.64±1.72)m L,低于对照组的(6.98±3.02)m L,差异有统计学意义;治疗组的患者宫颈平均愈合时间为(1.12±0.34)个月,低于对照组的(1.24±0.41)个月,但差异无统计学意义;治疗组的患者无一例发生宫颈子宫内膜异位症,对照组共4例患者发生子宫内膜异位症;治疗组宫颈子宫内膜异位症的发生率低于对照组,差异有统计学意义;观察组患者服药期间均无阴道出血,分泌物正常,对照组患者3例发生阴道点滴出血,1例患者阴道出现脓性分泌。结论:去氧孕烯炔雌醇可以减少术中出血量,缩短物理治疗后宫颈愈合时间,减少宫颈子宫内膜异位症的发生率,起到预防子宫内膜异位症的作用。且去氧孕烯炔雌醇的不良反应轻微,值得在临床工作中推广、应用。
Objectives:To investigate the effect of desogestrel and ethinylestradiol in preventing cervical endometriosis;to summarize the clinical experience to provide a theoretical basis for future prevention and treatment of these patients.Methods:68 cervical erosion patients receiving routine physical treatment from June 2011 to June 2013 were selected and randomly divided into two groups:control group of 34 patients to receive postoperative anti-biotic therapy;treatment group of 34 patients to receive additional desogestrel and ethinylestradiol for two months o-rally.The blood loss,postoperative healing time of the cervix,cervical endometriosis occurrence of the two groups was compared.Results:The mean blood loss for patients in the treatment group (4.64 ±1.72)mL was lower than the control group (6.98 ±3.02)mL,with statistically significant difference;the average healing time of cervix in the treatment group (1.12 ±0.34 months)was lower than the control group (1.24 ±0.41)months,without sta-tistically significant difference;there was no case of cervical endometriosis in the treatment group,but a total of four cases in the control group,with statistically significant difference in the incidence of cervical endometriosis;no vagi-nal bleeding during medication in the observation group with normal secretions,but there were three cases of vaginal spotting and one case of purulent vaginal secretion in the control group.Conclusion:Desogestrel and ethinylestradi-ol can reduce blood loss,shorter healing time after cervical physical therapy and reduce the incidence of cervical en-dometriosis,thusly preventing endometriosis.Meanwhile,desogestrel and ethinylestradiol is of slight adverse reac-tion,worthy promotion and application in clinic.
出处
《中国性科学》
2015年第5期32-34,共3页
Chinese Journal of Human Sexuality
基金
浙江省苍南县科技计划项目(2013S53)