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低分子肝素钙预防肺癌化疗患者静脉血栓形成的价值及可行性 被引量:2

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摘要 目的探讨低分子肝素钙预防肺癌化疗患者静脉血栓形成的价值及可行性。方法将176例肺癌化疗患者随机分为对照组和观察组各88例,对照组不进行抗凝治疗,观察组给予低分子肝素钙抗凝治疗,对比两组静脉血栓栓塞发生率、凝血功能及安全性。结果观察组静脉血栓栓塞发生率为3.41%,低于对照组的21.59%,差异有统计学意义(P〈0.05);对照组治疗后各项凝血功能指标均较治疗前明显升高,观察组治疗后各项指标均较治疗前明显降低,治疗后观察组各项指标均明显低于对照组,差异有统计学意义(P〈0.05);两组安全性差异无统计学意义(P〈0.05)。结论低分子肝素钙可有效改善肺癌化疗患者的高凝状态,降低静脉血栓栓塞的发生率,且不增加出血风险,值得临床推广使用。
作者 杜敏
出处 《中国实用乡村医生杂志》 2015年第9期61-63,共3页 Chinese Practical Journal of Rural Doctor
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