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MicroRNAs in tumor stem cells

MicroRNAs in tumor stem cells
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摘要 Micro RNAs(mi RNAs) are a class of non-coding RNAs that are believed to have a significant role in tumorigenesis and cancer metastasis. Cancer stem cells play a major role in tumor recurrence, metastasis, and drug resistance. Research has shown that mi RNAs can promote or inhibit the stemness of cancer stem cells and regulate the differentiation and self-renewal of cancer stem cells. In this article, the phenotype and regulatory mechanisms of mi RNAs in cancer stem cells will be described, together with an explanation of their potential role in tumor diagnosis and treatment. MicroRNAs (miRNAs) are a class of non-coding RNAs that are believed to have a significant role in tumorigenesis and cancer metastasis. Cancer stem cells play a major role in tumor recurrence, metastasis, and drug resistance. Research has shown that miRNAs can promote or inhibit the sternness of cancer stem cells and regulate the differentiation and self-renewal of cancer stem cells. In this article, the phenotype and regulatory mechanisms of miRNAs in cancer stem cells will be described, together with an explanation of their potential role in tumor diagnosis and treatment.
机构地区 Department of Oncology
出处 《The Chinese-German Journal of Clinical Oncology》 CAS 2015年第2期92-96,共5页 中德临床肿瘤学杂志(英文版)
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