超声造影评估老年2型糖尿病合并脑梗死患者颈动脉斑块稳定性的临床价值

Assessing stability of carotid artery plaques in elderly type 2 diabetic patients with cerebral infarction using contrast-enhanced ultrasonography

目的探讨超声造影检查对老年2型糖尿病合并脑梗死患者颈动脉斑块进行评价的临床意义。方法 96例老年2型糖尿病患者根据是否合并脑梗死分为两组:糖尿病合并脑梗死组(DMCI组)53例,糖尿病无脑梗死组(DMNCI组)43例。所有患者均行超声造影,记录颈动脉斑块厚度、斑块达峰时间和斑块增强强度,并对两组进行比较分析。结果 DMCI组斑块厚度与DMNCI组比较差异无统计学意义(P>0.05)。DMCI组斑块达峰时间较DMNCI组时间延长、斑块增强强度高于DMNCI组,差异均有统计学意义(均P<0.01)。结论超声造影能无创、定量地评价斑块的性质及增强状况,根据增强情况对斑块的易损性进行可视化定量评估,对临床治疗具有重要的指导意义。

Objective To investigate the clinical value of assessing the stability of carotid artery plaques in elderly type 2 diabetic patients with cerebral infarction using contrast-enhanced ultrasound. Methods Ninety six elderly patients with type 2 diabetes were enrolled in the study, including 53 cases complicated with cerebral infarction （DMCI group）, and 43 cases without cerebral infarction （DMNCI group）. All patients underwent contrast-enhanced ultrasonic examinations; and the thickness, peak time and enhanced strength of plaques was documented and compared between two groups. Results There was no sig- nificant difference in the thickness of plaque between DMCI and DMNCI groups （P 〉0.05）. Compared with the DMNCI group, the peak time of plaque in DMCI group was longer, and the enhanced strength of plaque was higher （both P〈0.01）. Conclusion Contrast-enhanced ultrasonography can demonstrate the character and enhanced status of carotid artery plaques noninvasively and quantitatively, by which the vulnerability of plaque can be evaluated visually and quantitatively.