转化糖电解质注射液对结直肠肿瘤患者术中电解质及血糖的影响

Effects of invert sugar and electrolytes injection on the blood glucose and electrolyte of patients with colorectal cancer during operation

目的观察转化糖注射液对结直肠肿瘤患者术中电解质及血糖的影响。方法 60例ASAⅠ~Ⅱ级择期行全麻下结直肠癌根治术的患者,随机分为两组,观察组（转化糖注射液组）和对照组（乳酸钠林格氏液组）,每组30例。患者入室后开通中心静脉即开始输注：治疗组输注10%转化糖注射液250ml,对照组输注乳酸钠林格注射液250ml,输注时间30分钟。分别于输液前（T0）,液体滴完0分钟（T1）、30分钟（T2）、1小时（T3）、2小时（T4）抽取动脉血,行血气分析,记录电解质,血糖结果。结果观察组在T1、T2、T3时血糖较T0明显升高（P〈0.05）,但在T4时血糖与T0比较无显著差异（P〉0.05）;对照组血糖在输注乳酸钠林格氏液前后无明显变化。观察组患者给药后各时点钾离子水平无明显变化,钠离子水平较给药前明显降低,但均在正常范围内。观察组患者血糖水平在T1、T2、T3时点明显高于对照组,差异有显著性（P〈0.05）;观察组患者钾离子水平在T1、T2、T3、T4时点明显高于对照组,钠离子水平在T1、T2、T3、T4时点明显低于对照组,差异有显著性（P〈0.05）。结论转化糖电解质注射液能安全用于结直肠癌患者能量供给和电解质的平衡。

Objective To observe the effects of invert sugar and electrolytes injection on the blood glucose and elec-trolyte of patients with colorectal cancer during operation. Method 60 patients with colorectal cancer operation（ ASAⅠ~Ⅱ） were randomly divided into the observation group and the control group,30 cases in each group. Blood glu-cose and electrolytes before drops and 0 min, 30min,1 h and 2 h after drops were recorded. Result The level of blood glucose increased in observation group in T1、T2、T3 after infusion（P＆lt;0. 05）, but it almost recovered to the normal level in T4 . The blood glucose of the control group were not significant change after infusion. Na＋level in ob-servation group after drops were significantly lower than those before infusion and those in control group（P＆lt;0. 05）;K＋ level in observation group were not significant change after infusion, but higher than those in control group（ P＆lt;0. 05）. Conclusion The invert sugar injection is effective in providing energy and regulating electrolyte balance for patients with colorectal cancer during operation.