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地佐辛联合丙泊酚在老年患者无痛胃镜检查中的临床观察 被引量:16

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摘要 目的观察地佐辛联合丙泊酚用于老年患者无痛胃镜检查的有效性及安全性。方法 2011年3月至2014年5月行无痛胃镜检查的老年患者228例,随机分为地佐辛联合丙泊酚组(D/P组)和丙泊酚组(P组)各114例。D/P组麻醉:静脉注射地佐辛30μg/kg,密切观察10 min后注入丙泊酚1.5 mg/kg;P组麻醉:单纯静脉注射丙泊酚2 mg/kg。观察两组患者的血流动力学指标,记录两组丙泊酚用量、苏醒时间、定向恢复时间、满意程度及不良反应发生情况。结果两组均顺利完成检查。检查中两组平均动脉血压、血氧饱和度、呼吸频率、心率均有所下降,其中P组平均动脉血压、心率低于D/P组,差异有统计学意义(P均<0.05)。D/P组患者丙泊酚用量、苏醒时间均小于P组(P均<0.05);并发症发生率明显低于P组(6.1%vs 20.2%,P<0.05);患者满意程度高于P组(P<0.05)。结论地佐辛联合丙泊酚用于老年患者无痛胃镜检查,可稳定循环呼吸功能,安全性好,并提升患者的满意程度。
出处 《中国临床研究》 CAS 2015年第5期611-613,共3页 Chinese Journal of Clinical Research
基金 河南省医学科技攻关计划项目(201303173)
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