腹腔镜微创治疗胃肠间质瘤临床效果观察

Observation of clinical effect by laparoscopic minimally invasive treatment of gastrointestinal stromal tumor

目的观察腹腔镜微创治疗胃肠间质瘤（GIST）的效果与安全性。方法 30例经过胃镜联合检查的胃肠间质瘤患者采用微创治疗作为观察组,另选往期采用开腹治疗的胃肠间质瘤患者30例作为对照组,比较两组患者手术时间、术中出血量、术后排便时间、术后住院时间、围术期并发症及根治度,并进行统计学分析。结果观察组30例患者在腹腔镜联合胃镜治疗下均完成手术,且未出现死亡、中转开腹的现象,对照组30例手术均获成功。观察组患者手术时间、术中出血量、术后排便时间、术后住院时间与对照组比较差异均有统计学意义（P〈0.05）;观察组患者围术期并发症、根治度与对照组比较差异无统计学意义（P〉0.05）;经过2-24个月的成功随访,无肿瘤复发和远处转移现象出现。结论腹腔镜微创治疗胃肠间质瘤具有可行性,且临床效果较为满意,有恢复快、微创的优点,值得在临床广泛的推广应用。

ObjectiveTo observe the effect and safety of laparoscopic minimally invasive treatment of gastrointestinal stromal tumor （GIST）.MethodsThere were 30 gastrointestinal stromal tumor patients under gastroscope combined detection as observation group, and another 30 gastrointestinal stromal tumor patients under past laparotomy as control group. Comparisons were made on operation time, intraoperative bleeding volume, postoperative defecation time, postoperative hospital stay, perioperative complications, and eradication rate between the two groups for statistical analysis.ResultsAll 30 cases in the observation group received successful operation without any case of death or alternative laparotomy. Compared with the control group, the observation group had statistically significant differences of operation time, intraoperative bleeding volume, postoperative defecation time, and postoperative hospital stay （P〈0.05）. The differences of perioperative complications and eradication rate between the observation group and the control group all had no statistical significance （P〉0.05）. Follow-up lasting for 2-24 months showed no recurrent tumor or distant metastasis.ConclusionLaparoscopic minimally invasive treatment contains feasibility with satisfactory clinical effect. This method has advantages of quick recovery and small invasion, and it is worthy of widely clinical promotion and application.