期刊文献+

肠炎动物模型的研究进展 被引量:4

下载PDF
导出
摘要 为了研究某种疾病的发病机理或免疫反应原理,一般多在实验动物模型上进行,可以说免疫学的发展与实验动物科学的兴起有着密切的联系。目前,肠炎性疾病仍是世界性重大难题。肠炎根据病因不同,大体上可以分为细菌性肠炎、病毒性肠炎、抗生素相关性肠炎、炎症性肠病(Inflammatory bowel disease,IBD)等。为研究各种肠炎的发病机制及探索新的治疗药物,人们构建了许多动物模型。
出处 《中国免疫学杂志》 CAS CSCD 北大核心 2015年第5期704-706,共3页 Chinese Journal of Immunology
基金 国家自然科学基金资助项目(No.31372413)
  • 相关文献

参考文献25

  • 1Kim YS,Lee MH,Ju AS,et al. Thl7 responses are not induced in dextran sodium sulfate model of acute colitis [ J ]. Immune Network,2011,11 (6) :416-419.
  • 2Perse M, Cerar A. Dextran sodium sulphate colitis mouse model: Traps and tricks [ J ]. J Biomed Biotechno1,2012,12 ( 3 ) :718-730.
  • 3Laroui H,Ingemoll SA,Liu HC ,et al. Dextran sodiumsulfate(DSS) induces colitis inmiee by forming nanodipocomplexes with medium- chain-length fatty acids in the eolon[ J ]. PLoS One, 2012, 7 (3) : e32084.
  • 4Shi XZ, Winston JH, Sama SK. Differential immune and genetic responses in rat models of Crehn's colitis and ulcerative colitis [J]. Am J Physiol Gastrointest Liver Physiol, 2011,300 ( 1 ) : G41-G51.
  • 5Zhu MY,Lu YM,Ou YX,et al. Dynamic progress of 2,4,6-trini- trobenzene sulfonic acid induced chronic colitis and fibrosis in rat model[J]. J Dig Dis,2012,13(8) :421-429.
  • 6Ken-ichiro N, Ayako R, Kazuhiko K. Evaluation of the morpholog- ical changes of gastric raueosa induced by a low concentration ofacetic acid using a rat model[ J]. J Forensic & Legal Meal,2014, 22(2) :99-106.
  • 7Vinod PV, Guruvayoorappan C. Protective effect of marine mangrove Rhizophora apiculata on acetic acid induced experime- ntal colitis by regulating anti-oxidant enzymes, inflammatory mediators and nuclear factor-kappa B subunits [ J ]. Inter Immuno- phar,2014,18( 1 ) :124-134.
  • 8Shim DH, Suzuki T, Chang SY, et al. New animal model of shigellosis in the guinea pig: its usefulness for protective efficacy studies[ J 1. J Immunol,2007,178 (4) :2476-2482.
  • 9Chen W, Li J, Qu H, eta]. The melanocortin receptor (MCIR) inhibits the inflammatory response in Raw 264. 7 ceils and atopic dermatitis ( AD ) mouse model [ J ]. Mol Biol Rep, 2013,40 ( 2 ) : 1987-1996.
  • 10Kwang-il J, Malabi M, Vcnkatesan B, et al. Evaluation of virulent and live Shigclla sonnci vaccine candidates in a guotobiotic piglet model[ J]. Vaccine,2013,31 (37.) :4039-4046.

二级参考文献33

共引文献19

同被引文献47

引证文献4

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部