曲安奈德在玻璃体视网膜手术中的临床应用

Application of Triamcinolone acetonide in vitreoretinal surgery

目的 观察曲安奈德（triamcinolone acetonide）在玻璃体视网膜手术中临床应用的效果.方法 玻璃体视网膜术前、术中对于玻璃体后脱离未确定的100例（100眼）在玻璃体大部分切除之后注入曲安奈德混悬液2 mg,进行玻璃体染色,以便将玻璃体彻底清除.术中观察玻璃体残留情况,术后观察眼压、视网膜情况及并发症,随访3～4个月.结果 本组所有患者注入曲安奈德后,玻璃体残留情况均可完全认清,顺利完成玻璃体后脱离,并将玻璃体彻底清除.术后眼压升高6例,发生率为6.00％,经对症治疗后均得到控制.术后3～4个月随访,无白内障,无视网膜脱离复发病例.结论 曲安奈德在玻璃体视网膜手术中的应用,有利于充分认清、辨别、清除玻璃体,提高玻璃体清除率,降低术后并发症发生率和视网膜脱离的复发率.

Objective To observe the clinical application of triamcinolone acetonide in vitreoretinal surgery.Methods One hundred eyes of 100 patients in whom the posterior vitreous detachment was not disagnosed before and during the vitreoretinal surgery were chosed,and triamcinolone acetonide suspension 2 mg was injected to stain the vitreous after resection of most vitreous and then the posterior cortex of vitreous was completely removed.The vitreous residue and postoperative intraocular pressure was observed.Results Triamcinolone acetonide was injected in all patients and the residual vitreous can be fully recognized.The posterior vitreous detachment was completed,and the vitreous was thoroughly cleared.The postoperative high intraocular pressure happened in 3 cases,and the incidence rate was 6%.After symptomatic treatment,the high intraocular pressure was controlled and recovered.After following up for 3 ～ 4 months,no cataract or recurrent retinal detachment occurred.Conclusion Triamcinolone acetonide has high application value on vitreoretinal surgery,which is helpful to fully understand,identify and remove the vitreous,improve the vitreous clearance rate,reduce the incidence of postoperative complications and the recurrence rate of retinal detachment.