电话随访对乳腺癌患者内分泌治疗依从性及生命质量的影响

Influence of follow- up by telephone on adherence and quality of life for breast cancer patients with hormonal therapy

目的探讨电话随访对乳腺癌患者内分泌治疗依从性和生命质量的干预效果。方法将78例内分泌治疗的乳腺癌患者按随机数字表法随机分为干预组40例和对照组38例，干预组患者在常规治疗指导、嘱其定期复诊的基础上接受定期电话随访，对患者内分泌治疗期间的用药问题、心理问题等提供指导。对照组行常规护理，嘱其定期复诊；以乳腺癌患者内分泌治疗依从性问卷和癌症康复系统评价简表作为评价工具，分别在出院时、出院后6个月对干预效果进行评价。结果6个月后，生命质量方面，干预组得分为（25．43±6．04）分，对照组得分为（40．61±7．73）分，2组比较差异有统计学意义，P〈O．05；治疗依从性方面，干预组得分为（8．57±6．20）分，对照组得分为（14．12±6．63）分，2组比较差异有统计学意义，P〈O．05。结论电话随访能提高乳腺癌患者内分泌治疗依从性和生命质量，值得推广应用。

Objective To explore the influence of follow-up by telephone on adherence and quality of life for breast cancer patients with hormonal therapy. Methods Totally 78 breast cancer patients with hormonal therapy were divided into the intervention group （40 cases） and the control group （38 cases）. The control group were carried on routine guidance treatment and enjoined regular subsequent visit. The patients in intervention group were carried on the above-mentioned treatment and also receive regular follow- up by telephone. Through the follow-up by telephone we provided guidance for present and will present problems. Adherence for breast cancer patients with hormonal therapy and cancer rehabilitation evaluation system-short form（CARES-SF） were used to investigate the patients＇ adherence and quality of life six month after the intervention. Then we compared the adherence and quality of life before, six month of the intervention. The changes of adherence and quality of life scores were analyzed by repeated-measure ANOVA. Results The score of quality of life in the intervention group after 6 month of intervention was （25.43 ± 6.04）, while in the eontrol group was （40.6l ± 7.73） , the difference was significant between the two groups, P〈0.05. The score of medication adherence in the intervention group after 6 month of intervention was （8.57 ± 6.20）, while in the control group was （14.12 ±6.63） , the difference was significant between the two groups, P〈0.05. Conclusion Follow- up by telephone can improve adherence and quality of＂ life for breast cancer patients with hormonal therapy.