红花黄色素注射液对卧床患者凝血象及D-二聚体的影响

Clinical Studies of Safflor Yellow Pigment Effects on Coagulation and D-dimer of Bedridden Patients

目的:观察红花黄色素注射液联合低分子肝素钠对骨科卧床患者凝血象(APTT、PT)及D-二聚体的影响。方法:将48例患者随机分为两组,两组均采用常规皮下注射低分子肝素钠加上物理治疗,治疗组加用红花黄色素注射液静脉滴注,疗程为14 d,并检测凝血象(APTT、PT)及D-二聚体各项指标。结果:两组治疗后凝血象(APTT、PT)均较治疗前延长,差异有统计学意义(P<0.05);两组治疗后比较,治疗组APTT、PT均高于对照组(P<0.05),凝血象各指标均处于正常范围。两组治疗后D-二聚体均较治疗前增高,差异有统计学意义(P<0.05),对照组增高较治疗组明显。结论:红花黄色素注射液对卧床患者凝血象及D-二聚体有积极的影响。

Objective： To observe effects of safflower yellow injection combined Low molecular weight heparin sodium on Coagulation and d-dimer of bedridden patients. Methods： The totally 48 patients were randomly divided into two groups, all pa- tients were treated with conventional subcutaneous injection of low molecular heparin sodium and Physiotherapy, the treatment group with safflor yellow injection for 14 days; the patients were reviewed of deep venous ultrasound understand the situation and detect clotting as indicators. Results： After treatment, the coagulation （APTF and PT） increased in two groups, with statisti- cal difference （P〈0.05）. And the treated group showed higher APT＇F and PT than the control group（P〈0.05）; Clotting indexes were in normal range. The D-dimer increased in two groups after treatment, with statistical difference （P〈0.05）, and the change of treatment group was more obvious than the control group .Conclusion： Safflower yellow injection has a positive effect on Coag- ulation and d-dimer of bedridden patients.