自拟化湿散结汤治疗湿热毒瘀型结节性痒疹40例临床观察

Clinical Observation of Self-designed Huashi Sanjie Decoction on 40 Cases of Prurigo Nodularis with Damp-Heat and Toxic-Stasis Syndrome

目的观察自拟化湿散结汤联合西药治疗湿热毒瘀型结节性痒疹的临床疗效。方法将80例湿热毒瘀型结节性痒疹患者随机分为2组。对照组40例予西替利嗪及多虑平口服;观察组40例在对照组治疗基础上,加服中药自拟化湿散结汤治疗。观察比较两组治疗1个月后的临床疗效。结果观察组总有效率为92.5%,痊愈率为37.5%;对照组总有效率为75.0%,痊愈率为22.5%;两组比较差异有统计学意义(P<0.01)。结论自拟化湿散结汤联合西药治疗湿热毒瘀型结节性痒疹的临床疗效肯定,可以在临床上推广应用。

Objective To observe clinical efficacy of self-designed Huashi Sanjie decoction combined with western medicine in the treatment of damp-heat and toxic-stasis type prurigo nodularis. Methods 80 cases of prurigo nodularis patients with damp-heat and toxic-stasis syndrome were randomly divided into 2 groups. 40 cases in the control group were treated orally with cetirizine and doxepin. 40 cases in the observation group based on the treatment of control group were administrated with self-designed Huashi Sanjie Decoction. The clinical curative effect of two groups were observed and compared after 1 months of treatment. Results The total effective rate in the observation group was 92.5%, the cure rate was 37.5%; the total effective rate in the control group was 75%, the cure rate is 22.5%; there was significant difference between both groups （P〈0.01）. Conclusion The self-designed Huashi Sanjie decoction combined with western medicine in the treatment of damp-heat and toxic-stasis type prorigo nodularis is effective and can be widely used in the clinic.