加味升陷苓桂术甘汤治疗慢性阻塞性肺疾病急性加重期35例临床观察

Clinical Observation of Jiaweishengxian Linggui Zhugan Decoction on the Treatment of 35 Chronic Obstructive Pulmonary Patients

目的观察加味升陷苓桂术甘汤治疗慢性阻塞性肺疾病急性加重期的临床疗效。方法将70例慢性阻塞性肺疾病急性加重期患者随机分为对照组与治疗组,每组35例。对照组给予抗感染、化痰止咳平喘、氧疗等治疗;治疗组在对照组用药基础上加服加味升陷苓桂术甘汤,14 d/疗程。观察2组患者治疗前后的临床症状、肺功能、血气情况。结果对照组、治疗组总有效率分别为85.71%、94.29%,2组比较差异有统计学意义(P<0.05);2组在治疗1个疗程后肺功能均有明显改善,Pa O2明显升高,Pa CO2明显降低,且治疗组在改善肺功能和动脉血气方面优于对照组,差异有有统计学意义(P<0.05)。结论加味升陷苓桂术甘汤治疗慢性阻塞性肺疾病急性加重期具有较好疗效。

Objective： To observe the clinical effect of Jiaweishengxian Linggui Zhugan Decoction on the treatment of chronic obstruc- tive pulmonary patients. Methods： 70 patients were randomly divided into a control group and a treatment group, 35 cases per group. The control group was treated with antibiotics, antitussive and antiasthmatic prescriptions and oxygen therapy while the treatment group was add- ed with Jiaweishengxian Linggui Zhugan Decoction besides the treatment of the control group. 14 days was a course of treatment. The pa- tients＇ clinical symptoms, pulmonary function and blood gas of the two groups were observed before and after the treatment. Result ： The total effective rate of the control group and the treatment group was 85.71% and 94. 29% respectively. The comparison of the two groups was statistically significant difference （P 〈 0. 05）, The pulmonary function of the two groups after a course of treatment showed significant improvement, PaO2 increased significantly and PaCO2 decreased significantly. The treatment group improved better than the control group in the pulmonary function and arterial blood gas and the difference was statistically significant （ P 〈 0. 05 ）. Conclusion： Jiaweishengxian Linggui Zhugan Decoction has a good effect on the treatment of chronic obstructive pulmonary patients with acute exacerbation.