血液透析患者抑郁状态及其相关因素分析

Depression in hemodialysis patients and its impact factors

目的探讨终末期肾脏疾病(ESRD)血液透析患者抑郁的发生率及其影响因素。方法采用贝克抑郁量表(BDI)对124例ESRD血液透析患者进行抑郁状态评估,并比较抑郁组和非抑郁组的一般情况及实验室指标。结果 BDI评分显示纳入研究的患者抑郁的患病率为56.5%。抑郁组和非抑郁组比较,性别构成和就业情况的差异有统计学意义(P<0.05),女性和非在职患者抑郁情绪出现的概率较高;两组患者在年龄、透析时间、文化程度、婚姻状况、经济情况方面进行比较,差异均无统计学意义(P>0.05)。在实验室检查方面,抑郁组白细胞以及血尿酸水平均高于非抑郁组,差异有统计学意义(P<0.05)。结论 ESRD血液透析患者抑郁的发生率较且好发于女性和非在职患者,同时伴随较高的白细胞和尿酸水平。

Objective To investigate the prevalence of depression in hemodialysis patients with end‐stage renal disease（ESRD） , and evaluate its related factors .Methods One hundred and twenty four ESRD patients undergoing hemodialysis were assessed by using Beck depression inventory （BDI） .Baseline characteristics and laboratory test items were compared between depression group and non‐depression group .Results The prevalence of depression detected by BDI was 56 .5% in hemodialysis patients with ESRD . Gender and occupational status were statistically different between depression and non‐depression groups（P〈0 .05） .Higher preva‐lence was found among female and non‐working patients .However ,there was no difference on age ,hemodialysis time ,education , marriage and incoming（P〉0 .05） between the two groups .In laboratory test ,the white blood cell and urine acid levels in depression group were significant higher than that in the non‐depression group（P〈0 .05） .Conclusion Depression is prevalent in ESRD pa‐tients undergoing hemodialysis ,especially in female and non‐working patients and always combined with higher white blood cells and urine acid levels .