阿卡波糖联合二甲双胍治疗2型糖尿病30例临床观察

Clinical observation of acarbose combined with metformin in the treatment of 30 cases with type 2 diabetes

目的 :观察阿卡波糖联合二甲双胍治疗2型糖尿病的临床疗效和不良反应。方法 :选择2014年4月至5月南京西路社区卫生服务中心门诊的2型糖尿病患者60例,分为观察组和对照组各30例。观察组给予阿卡波糖和二甲双胍治疗,对照组维持单品种降糖药治疗。3个月后比较两组的治疗效果。结果 :观察组总有效率为83.3%(25/30),对照组为53.3%(16/30),两组比较差异有统计学意义(χ2=4.93,P<0.05)。两组不良反应差异无统计学意义(χ2=0.14,P>0.05)。结论 :阿卡波糖联合二甲双胍可以作为基层医院治疗2型糖尿病的选择。

Objective： To observe the clinical efficacy and adverse reaction of acarbose combined with metformin in the treatment of type 2 diabetes. Methods： Sixty cases of type 2 diabetes were selected in Nanjing West Road Community Health Service Center from April to Mary 2014, and divided into an observation group and a control group with 30 cases each. The observation group received the treatment of acarbose and metformin, and the control group maintained a single hypoglycemic treatment. The treatment effect between two groups was compared after 3 months. Results： The total effective rate was 83.3% （ 25/30 ） in the observation group and 53.3% （ 16/30 ） in the control one, and the comparison difference between two groups had the statistical significance （ χ^ 2=4.93, P 〈 0.05）. The difference of the adverse reaction between two groups had no significant difference （χ^2=0.14, P 〉 0.05）. Conclusion： Acarbose combined with metformin can be used as a grass-roots hospital choice for the treatment of type 2 diabetes.