中西医结合治疗膝骨性关节炎疗效分析及不良反应观察

Curative Analysis and Adverse Reactions Observation of Applying Integrative Medicine to Treat Knee Arthritis

目的:观察膝骨性关节炎应用中西医结合治疗疗效及不良反应发生情况。方法:本组92例患者根据随机数字表法将其随机分为观察组(n=46)和对照组(n=46)。对照组给予曲安奈德注射液治疗,观察组在对照组基础上结合中药汤剂治疗。两组患者均以3周为1个疗程,连续治疗2个疗程。结果:观察组总有效率(93.48%)显著高于对照组(73.91%)(P<0.05),观察组治疗后VAS评分显著低于治疗前及对照组治疗后(P<0.05),观察组治疗后膝关节功能评分显著高于治疗前及对照组治疗后(P<0.05),观察组治疗后滑膜厚度、关节腔积液积分显著低于治疗前及对照组治疗后(P<0.05),两组患者治疗过程中均未发生明显的不良反应。结论:膝骨性关节炎应用中西医结合治疗疗效显著,且无明显不良反应,具有重要临床研究意义。

Objective： To investigate the therapy efficacy and adverse events of applying integrative medicine to treat knee osteoarthritis. Methods： According to the random number table, 92patients were randomly divided into two groups： observation group （n = 46 ） and controlled group （n = 46 ）. The controlled group received triamcinolone acetonide injection treatment, the observation group combined decoction treatment on the basis of the controlled group. The two groups of patients were three weeks for a course of treatment, continuous treatment of two courses. Results： The total effective rate （93.48%） of the observation group was significantly higher （73.91% ） （P〈0.05） than the controlled group, VAS score was significantly lower than before the treat- ment and the controlled group after treatment （ P〈0. 05 ）, the observation group after the treatment of knee function score was significantly higher than that before treatment and after treatment in the controlled group （ P〈0.05 ）, the observation group after treatment synovial thickness, joint effusion integration was significantly lower than the controlled group before treatment and after treatment （ P〈0. 05 ） during the treatment of patients in both groups were not significant adverse reactions. Conclusion ： The application of knee osteoarthritis in combination therapy effect is significant, and no significant adveme reactions, has important clinical significance.