静电纺丝素蛋白与无机物复合纳米材料的研究进展

Progress in the Electrospun Silk Fibroin and Inorganic Matter Nanocomposite Materials

利用静电纺丝技术制备再生丝素纳米纤维具有高比表面积、高孔隙率以及良好的生物相容性的优势,所以广泛应用于生物材料和组织工程等领域。单一的再生丝素纳米纤维脆性大,力学性能差,而采用由不同的无机粒子或合成高聚物与丝素共混制备复合纳米纤维可以极大地改善单纯使用一种材料的适应性,并且使复合纤维同时具备多种优势。本文综述近年来国内外静电纺丝制备再生丝素与无机粒子或合成高聚物复合纳米纤维的研究现状,旨在为提高丝素纳米纤维的综合性能,拓展其应用。

Regeneration Bombyx mori （B.mori） silk fibroin （SF） nanofibers prepared by electrospinning were widely ap- plied in in the fields of biomaterials and tissue engineering, with the advantages of high specific surface area, high poros- ity, and good biocompatibility. Pure regenerated SF nanofibers were fragile and poor in mechanical performance, howev- er the composite nanofibers synthesized by blending different inorganic particles or synthetic polymers into SF has much more advantages for it can greatly improve the suitability compared with which of a single material. This paper summa- rized preparation of SF and inorganic particles or synthetic polymers composite nanofibers in the domestic and at abroad in recent years, which aims to improve the comprehensive performance of SF nanofibers and expand its application.