中西医结合治疗胰腺炎疗效观察

Effects Observation of Integrated Medicine on Pancreatitis

目的:研究生长抑素联合中药方剂治疗胰腺炎疗效,为临床治疗提供参考依据。方法:抽取我院2012年4月—2015年4月胰腺炎患者90例,进行分组研究。按照随机分组原则,分为中西医治疗组和西医治疗组,每组45例。中西医治疗组采用生长抑素联合中药方剂治疗,西医治疗组采用生长抑素治疗。对比两组患者治疗效果、不良现象发生率、临床实验指标恢复正常时间情况。结果:中西医治疗组药物治疗总疗效明显高于西医治疗组,差异有统计学意义(P<0.05);中西医治疗组不良现象发生率跟西医治疗组无显著差异(P>0.05)。两组患者临床症状及实验室指标恢复至正常时间相比较:中西医治疗组患者血淀粉酶、尿淀粉酶、C反应蛋白检测值恢复正常及患者腹痛缓解等时间均短于西医治疗组P<0.05。结论:生长抑素联合中药方剂治疗胰腺炎疗效显著,跟单用生长抑素对比,药物治疗总疗效高,有利于促进临床指标改善,且用药具有较高的安全性,可克服单独西医治疗的缺陷,值得推广。

Objective To explore effects of somatostatin combined with herbal medicine formula on pancreatitis and to provid reference for clinical treatment. Methods： 90 cases of pancreatitis treated in our hospital from April 2012 to April 2015 were randomlydivided into integrated medicine treatment group （IMTG） and western medicine treatment group （WMTG）, each of 45 cases. The IMTGwas given somatostatin combined with herbal medicine while the WMTG was treated with somatostatin. And we compared the effects,adverse effects occurrence and the time consumed of clinical and laboratory indicators returning to normal. Results： The total efficiency ofthe IMTG was significantly higher than that of the WMTG, with difference of statistic significance （P〈0.05）; the adverse effectsrecurrence of the IMTG showed no difference from those of the WMTG （P〉0.05）. We compared the time consumed of clinical symptomsand laboratory indicators returning to normal： the time consumed of S-AMY, U-AMY and C-creative protein returning to normal andabdominal pain relief etc. was shorter than that of the WMTG （P〈0.05）. Conclusion： Somatostatin combined with herbal medicineformula shows significant effects. And compared to simple medication of somatostatin, the total efficiency of medicine was much higher. Itimproves clinical indicators and overcomes simple medicine treatment with higher safety, which deserves clinical promotion.