丙种球蛋白治疗新生儿溶血症的临床研究

Clinical Study on Gamma Globulin in Treatment of New-born Patients of Hemolytic Disease

目的：分析新生儿溶血症给予丙种球蛋白的治疗效果。方法选取本院新生儿科2014年1月～2015年1月收治的45例新生儿溶血症患儿，按照随机数表法分为甲组和乙组，甲组采用常规药物治疗，乙组在甲组的基础上给与丙种球蛋白治疗，对比治疗效果。结果两组比较，乙组患儿的治疗总好转率为91.3%高于甲组的81.8%，并且乙组的血清总胆红素TBIL和血红蛋白水平Hb低于甲组，P＜0.05，差异具有统计学意义。结论新生儿溶血症严重威胁着患儿的健康，采用丙种球蛋白的治疗效果显著，患儿的痊愈率高，临床治疗意义大。

Objective To explore the effect on gamma globulin in treatment of new-born patients with hemolytic disease. Methods Selected 45 new-born patients with hemolytic disease from January 2014 to January 2015 in our hospital and divided them into Group A and Group B. patients in Group A were given conventional medication treatment, while patients in Group B were given additional gamma globulin treatment and then compared treatment effects between two groups. Results Patients’ treatment improvement rate in Group B was 91.3% higher than 81.8% the Group A,besides, patients’ total serum bilirubin of TBIL and hemoglobin Hb level in Group B were lower than counterparts in Group A, P〈0.05, had difference statistically significance. Conclusion Hemolytic disease is a serious threat to children’s health, while, gamma globulin is of efifcacy in treatment of children patients with hemolytic disease.