急性心肌梗死后心率变异性和心源性猝死危险性的关系

The relationship between heart rate variability and the risk of sudden cardiac death after acute myocardial infarction

目的:探讨急性心肌梗死(AMI)的心率变异性(HRV)与心源猝死(SCD)风险的相关性.方法:选择2010-06/2014-06间我院接收的35例AMI后SCD患者和同期体检健康者35例作回顾性研究,对比观察两组人群的临床HRV相关指标数据的差异.探讨临床AMI后的SCD患者的HRV各指标特征,为临床预后提供参考依据.结果:同健康者相比,发生AMI后猝死患者的全窦性心搏RR间期标差(SDNN)、RR间期平均标差(SDANN)、RR间期邻差方根(RMSSD)、50瑚以上NN期邻差百分比(PNN50)与低高频比值(LF/HF)等HRV指标数据值均显著更低(P<0.05).结论:AMI后发生SCD者的HRV各项指标数据与健康者间存在明显差别,在临床诊断中可根据受检者的HRV数据特征对其发生SCD的风险进行预测,可起到降低临床中SCD发生率及加强AMI预后的作用.

AIM： To study the correlation of of heart rate variability （HRV） and risk of sudden cardiac death （SCD） after acute myocardial infarction （AMI）. METHODS： Select 35 cases of patients with SCD after AMI received in our hospital and other 35 healthy persons as research object retrospectively from June 2010 to June 2014, differences of related indexes of clinical HRV were observed and compared between the two groups. Explore HRV parameters in patients with SCD after AMI, and provide the reference to clinical prognosis. RESULTS： Compared with healthy people, the HRV indexes SDNN, SDANN, RMSSD, PNN50 and LF/HF in patients with sudden death after AMI were significantly lower （P 〈 0.05）. CONCLUSION： There are obvious differences in HRV indexes between patients with SCD after AM and healthy people. And the occurrence risk of SCD can be predicted based on the characteristics of HRV data in clinical diagnosis, which can reduce the occurrence rate of SCD in the clinical prognosis and strengthen prognosis after AMI.