健脾益气汤治疗功能性消化不良随机平行对照研究

Parallel Randomized Controlled Study Jianpiyiqi Functional Dyspepsia Treated

[目的]观察健脾益气汤治疗功能性消化不良疗效。[方法]使用随机平行对照方法,将50例住院患者按病志号抽签法简单随机分为两组。对照组25例多潘立酮,10mg/次,3次/d。治疗组25例健脾益气汤(党参25g,黄芪50g,半夏12g,桂枝13g,苏梗、厚朴、香附各12g,大枣8g,茯苓、甘草炙各12g;肝气犯胃加栀子10g,丹皮12g;腹痛加白芍12g,川椒8g),浸泡30min,水煎200m L,早晚口服。连续治疗14d为1疗程。观测临床症状、消化功能、症候评分、不良反应。连续治疗4疗程,判定疗效。[结果]治疗组显效18例,有效6例,无效1例,总有效率96.00%。对照组显效11例,有效6例,无效7例,总有效率68.00%。治疗组疗效优于对照组(P<0.05)。症候评分两组均有降低(P<0.05),治疗组改善优于对照组(P<0.01)。[结论]健脾益气汤治疗功能性消化不良疗效满意,无严重不良反应,值得推广。

[Objective]To observe the Spleen Qi Tang treatment of functional dyspepsia. [Methods]Using random parallel control method, 50 cases of hospitalized patients by disease Zhi No. ballot method is simple and randomized into two groups. The control group 25 cases domperidone, 10 mg / times, 3 times / d. Treatment group 25 cases of Spleen Qi Tang（Dangshen 25 g, Huangqi 50 g, Banxia12 g, Guizhi 13 g, Sugeng,Houpu,Xiangfu each 12 g,Dazao8g, Fuling,Gancao each 12g; Fan Wei Qi plus Zhizi 10 g, Danpi 12g; abdominal pain plus Baishao 12 g, Chuanjiao 8g）, soak 30 min, decoction 200 m L, sooner or later orally. 14 d is a continuous course of treatment. Observation of clinical symptoms, abdominal pain, adverse reactions. Continuous treatment four courses, determine efficacy. [Results] treatment group 18 cases, effective in 6 cases, one case, the total efficiency of 96.00%. Control group, 11 cases markedly effective in 6 cases, seven cases, the total efficiency of 68.00%. Treatment group than the control group（P0.05）. TCM symptom score reduced in both groups（P0.05）, improvement in the treatment group than the control group（P0.01）. [Conclusion] Spleen Qi Tang treatment of functional dyspepsia effect is significant, it is worth promoting.