温阳补阴活血汤联合二甲双胍治疗阴阳两虚兼血瘀型糖尿病平行对照研究

Tongluo an Chang Decoction for the Treatment of Emotional Upset Diarrhea Type Irritable Bowel Huoxue Compound Yin Yang and Yin and Yang Metformin and Blood Stasis Type Parallel-Group Study of Diabetes Treatment

[目的]观察温阳补阴活血汤联合二甲双胍治疗阴阳两虚兼血瘀型糖尿病疗效。[方法]使用随机平行对照方法,将120例住院患者按病志号抽签方法简单随机分为两组。对照组60例二甲双胍,0.5g/次,1次/d。治疗组60例温阳补阴活血汤(熟地黄20g,山茱萸、丹皮、茯苓各15g,附子10g,山药、泽泻各15g,桂枝10g,当归、川芎、红花各15g等),1剂/d,水煎300m L,3次/d;二甲双胍治疗同对照组。连续治疗45d为1疗程。观测临床症状、血糖、糖化血红蛋白、不良反应。治疗1疗程,判定疗效。[结果]治疗组显效48例,有效8例,无效4例,总有效率93.33%。对照组显效32例,有效16例,无效12例,总有效率80.00%。治疗组疗效优于对照组(P<0.05)。[结论]温阳补阴活血汤联合二甲双胍治疗阴阳两虚兼血瘀型糖尿病,疗效满意,无严重不良反应,值得推广。

[Objective] To observe the yang and yin Huoxue Compound metformin therapy yin and yang and blood stasis diabetes treatment. [Method] Randomized parallel-group method using the 120 cases of hospitalized patients by disease Zhi No. balloting were randomly divided into two groups. 60 cases in the control group diet, adequate exercise, use of antidiabetic drugs metformin to control blood sugar. Treatment group, 60 patients yin yang and promoting blood circulation traditional Chinese medicine, Rehmannia, dogwood, Dan, Poria,aconite, yam, Alisma, Gui, angelica root, safflower fry decoction, 100 m L/time, 3 times/d,orally;Western medicine with the control group. Continuous treatment for 45 days for a course of treatment. Clinical symptoms, blood glucose, glycosylated hemoglobin values, adverse reactions. [Results] treatment group 48 cases, 8 cases, 4 cases, the total efficiency of 93.33%. The control group 32 cases markedly effective in 16 cases, 12 cases, the total efficiency of 80%. Treatment group than in the control group（P〈0.05）. [Conclusion] Yang and Yin and promoting blood circulation traditional Chinese medicine combined with metformin and blood stasis diabetes Yin and yang effect is significant, worthy of promotion.