通腑化浊方联合西药治疗早期缺血性脑中风随机平行对照研究

Early Ischemic stroke Randomized Parallel Group Study Relaxing Huazhuo Prescription Combined Western Medicine

[目的]观察通腑化浊方联合西药治疗早期缺血性脑中风疗效。[方法]使用随机平行对照方法,将96例住院患者按抽签法简单随机分为两组。对照组48例保持呼吸道通畅,预防吸入性肺炎,抗凝剂,早期溶栓,抗血小板聚集。治疗组48例通腑化浊方（生大黄6~10g,菖蒲20g,郁金15g,胆南星制、丹参各15g,地龙15g,桃仁、天麻各12g,黄芪、瓜萎各30g,全蝎粉冲服1g,水蛭粉冲服1g,三七粉冲服3g）,1剂/d,水煎200m L,早晚口服;西药治疗同对照组。连续治疗4d为1疗程。观测临床症状、FMI评分、NIHSS评分、Ashworth评分、不良反应。连续治疗6疗程,判定疗效。[结果]治疗组痊愈12例,显效23例,有效13例,无效2例,总有效率95.83%。对照组痊愈2例,显效4例,有效10例,无效32例,总有效率33.33%。治疗组疗效优于对照组（P〈0.01）。指标评分两组均有改善（P〈0.01）,治疗组改善优于对照组（P〈0.05,P〈0.01）。[结论]通腑化浊方联合西药治疗早期缺血性脑中风疗效满意,无严重不良反应,值得推广。

[Objective]To observe Relaxing Huazhuo western medicine prescription combined effect of early ischemic stroke. [Methods] Uses random parallel control method, 96 cases of hospitalized patients with treatment order number method is simple and randomly divided into two groups. 48 cases in the control group to keep the airway open and prevent aspiration pneumonia, anticoagulants, early thrombolysis, anti-platelet aggregation. Relaxing treatment group 48 cases Huazhuo party（Shengdahuang 6 ~ 10 g, Changpu 20 g, Yujin 15 g, Dannanxing,Danshen 15 g, Dilong 15 g, Taoren,Tianma 12 g, Huangqi,Goulou each 30 g, Quanxiefen 1g, Shuizhifen 1g,Sanqifen 3g）, 1 a / d, decoction 200 m L, sooner or later oral; Western medicine with the control group. 4d continuous treatment for a course of treatment. Observation of clinical symptoms, FMI score, BI score, NIHSS score, Ashworth score, adverse reactions. 6 courses of continuous treatment, to determine efficacy. [Results] The cure 12 cases, 23 cases markedly effective in 13 cases, 2 cases, the total efficiency of 95.83%. Recovered two cases in the control group, effective in 4 cases, 10 cases, 32 cases, the total efficiency of 33.33%. Treatment group than in the control group（P〈0.01）. Index scores were improved in both groups（P〈0.01）, the treatment group than the control group improvement（P〈0.05, P〈0.01）. [Conclusion] Relaxing Huazhuo side combined with western treatment of early ischemic stroke results were satisfactory, no side effects, it is worth promoting.