健脾益肺祛痰方对支原体肺炎患儿炎症因子及免疫功能的影响

Effects of Jianpi Yifei Qutan Fang(健脾益肺祛痰方) on Inflammatory Factors and Immunological Function of Child with Mycoplasma Pneumonia

目的:探讨健脾益肺祛痰方对支原体肺炎患儿炎症因子及免疫功能的影响。方法:将80例支原体肺炎患儿随机分为观察组和对照组各40例。对照组给予常规对症治疗;观察组在对照组治疗基础上给予健脾益肺祛痰方口服,疗程两周。治疗前后采用ELISA法检测两组血清IL-2、IL-4、IL-6含量,用血浆蛋白分析仪速率散射比浊法检测Ig A、Ig G、Ig M和补体(C3、C4)水平。结果:治疗前两组各观察指标无差异(P>0.05),治疗后炎症因子水平明显改善,血清抗炎因子IL-2、IL-4含量明显增加,IL-6水平明显降低。免疫功能指标明显增高,与治疗前比较有统计学意义(P<0.05);组间比较,观察组炎症因子以及免疫指标改善均优于对照组(P<0.05)。结论:健脾益肺祛痰方可以调节支原体肺炎患儿炎症因子水平,提高患儿的免疫功能。

Objective：To explore the effects of Jianpi Yifei Qutan Fang on inflammatory factors and immuno- logical function of child with mycoplasma pneumonia. Methods ：80 Cases with mycoplasma pneumonia were ran- domly divided into observation group and control group, each group contained 40 cases. Control group was given routine treatment, observation group was given Jianpi Yifei Qutan Fang on the basis of control, treatment course was 2weeks. The serum IL -2, IL -4 and IL -6 contents were determined by ELISA method, IgA, IgG, IgM and complement C3, C4 were determined by rate scattering turbidimetry method with plasma protein analyzer. Re- sults：There was no difference between the two groups on the observation indexes before treatment, serum inflam- matory factors were obviously improved after treated in the two groups, immunologic function indexes were raised significantly, there were statistical significance to compare with pro -treatment（ P 〈 0.05 ）, the effects of obser- vation were better than those of control, the differences were statistical significance （ P 〈 0. 05 ）. Conclusion： Jianpi Yifei Qutan Fang can regulate the inflammatory factors and increase the immunologic function of child with mycoplasma pneumonia.