摘要
目的:通过对湖北民族学院附属民大医院上报的药品不良反应(ADR)及相关因素进行分析,了解药品不良反应发生特点,为临床安全用药提供依据。方法:收集该院2012年1月至2014年10月上报的200例ADR报告,对发生ADR的患者年龄、药品类别、用药途径、发生部位以及新发严重ADR的用药信息及转归等情况进行汇总统计分析。结果:ADR可涉及任意年龄阶段,静脉给药方式是引起ADR的主要途径,涉及药物以抗感染药物、中药注射剂为主,临床表现以皮肤及其附件损害的表现多见。新发严重ADR多发生在有过敏史的患者,且联合用药品种较多。结论:关注婴幼儿、老人及过敏体质者等特殊人群、减少静脉给药的比例、避免过度使用抗菌药物、规范中药注射剂使用等,是该院规避用药风险、减少ADR发生的重要措施。
OBJECTIVE：To analyze the related factors of the adverse drug reactions （ADRs） in Hubei University for Nationalities Affiliated Minda Hospital so as to probe into the characteristics of the ADRs for clinical reference of safe medication. METHODS： A total of 75 ADR cases reported from January 2012 to October 2014 in this hospital were analyzed with regard to patients＇ age, drug type, routes of administration, ADR-involved organs or systems, and medication information and outcomes of the new and severe ADR cases. RESULTS： The ADRs occurred in different age group, and induced mostly by intravenously administered drugs, by anti-infective drugs and traditional Chinese medicine injections, and manifested mostly by the damage of skin and its appendages. The new and serious ADR occurred more often in patients with a history of allergy and in thosev treated with combination of muhiple drugs. CONCLUSION ： To avoid the risk of medication and reduce the occurrence of ADR in this hospital, it is important to attach great importance to the special population including the infants and elderly and those with hypersensitivity, reduce the ratio of intravenous administration, avoid excessive use of antimicrobial drugs and regulate the use of traditional Chinese medicine injections.
出处
《中国医院用药评价与分析》
2015年第4期535-538,共4页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
药品不良反应
报告
分析
Adverse drug reactions
Report
Analysis
