摘要
The mammal gut microbiota has been called＂a hidden-organ＂.About 99%of the intestinal bacteria belong to anaerobic bacteria in both human and animals.Most of Chinese materia medica（CMM）are given via oral route in clinic.Hence,the drug metabolism in gut microbiota draws increasing attentions.After interacting with the gut bacteria,the biological effects of drugs might be altered,leading to toxicity（amygdalin,et al）or detoxification（aconitine,et al）,
The mammal gut microbiota has been called＂a hidden-organ＂.About 99%of the intestinal bacteria belong to anaerobic bacteria in both human and animals.Most of Chinese materia medica（CMM）are given via oral route in clinic.Hence,the drug metabolism in gut microbiota draws increasing attentions.After interacting with the gut bacteria,the biological effects of drugs might be altered,leading to toxicity（amygdalin,et al）or detoxification（aconitine,et al）,
