探讨丙种球蛋白联合地塞米松治疗小儿急性特发性血小板减少性紫癜的效果

The Effect of Gamma Globulin and Dexamethasone on Children with Acute Idiopathic Thrombocytopenic Purpura

目的分析丙种球蛋白与地塞米松的联合疗法在急性特发性的血小板减少性紫癜患儿治疗中的效果。方法选取200例急性特发性血小板减少性紫癜患儿,按照随机的方式将其列入观察组与对照组,每组各为100例。对照组使用地塞米松,而观察组则在对照组的基础上使用丙种球蛋白进行治疗。结果两组治疗有效率和症状缓解时间相比,观察组均要显著优于对照组,比较差异有显著性的统计学的意义(P<0.05);两组均无显著性的不良反应。结论在小儿急性特发性血小板减少性紫癜的治疗中应用丙种球蛋白与地塞米松的联合疗法可以优化治疗效果。

Objective Analyze the effect of gamma globulin and dexamethasone on children with acute idiopathic thrombocytopenic purpura. Methods Select 200 cases of children with acute idiopathic thrombocytopenic purpura, according to the random way in its list of observation group and control group, 100 cases in each gToup. Control group using dexamethasone, while in the control group on the basis of the observation group treated with ivig. Results Compared two groups of treatment efficient and symptoms of time, the observation group were significantly superior to control group, with sigmificant diffcrence comparing the statistical significance （ P〈0.05 ） ; Two groups had no significant adverse reactions. Conclusion During the treatment on children with acute idiopathic thromhocytopenic purpura, gamma globulin and dexamethasone can promote the treatment effect, and it deserves pronmtion.