病毒性脑炎后继发性癫痫的临床特点及药物疗效分析

Analysis of the Clinical Features of Secondary Epilepsy and Drug Efficacy After Viral Encephalitis

目的分析病毒性脑炎（VE）后继发性癫痫临床特点、药物疗效。方法回顾性分析23例VE后继发性癫痫患者病历资料。结果治疗后好转7例、无效15例、加重1例。随访12个月,每日发作1例、每周发作10例、每月发作2例,12个月内发作2-3次2例。结论不同VE后继发性癫痫病程、年龄、继发时间、有无先兆、癫痫发作时间、脑电图表现、疗效存在较大差异;VE治愈率低,药物治疗不能抱有太大的预期,特别是对于病毒侵袭范围较广、未发生病灶者,治愈率较低;对于疾病得到控制者,也应做好自我管理,规避诱发因素。

Objective Analysis of the clinical features of secondary epilepsy and drug efficacy after viral encephalitis（VE）. Methods A retrospective analysis of medical records of 23 cases of patients with epilepsy secondary after VE. Results After treatment, 7 cases were improved, 15 cases with ineffective, aggravated in l cases, follow-up of 12 months, one case with seizures daily, weekly episodes of 10 cases, and two cases of seizures per month. Seizures within 12 months were 2-3 times of 2 cases. Conclusion The age, course of＇disease and secondaty time, with or without aura, seizures, the electroencephalogram, effect of treatment in diff＂rent secondary epilepsy after VE have great diffrence; the cure rate of VE is low, the drug treatment can not have too high expectations, especially for viruses in wide range, without the occurrence of lesions, the cure rate is low; for the disease under control, we should also do a good job of self management, avoid inducing factors.