中西医结合治疗慢性阻塞性肺疾病临床观察

To Observe the Clinical Effect of Integrated Traditional and Western Medicine on Chronic Obstructive Pulmonary Disease at Acute Exacerbation Stage

目的:观察中西医结合治疗慢性阻塞性肺疾病急性加重期患者的临床疗效。方法:选取100例慢性阻塞性肺部疾病急性加重期患者,随机分为治疗组和对照组各50例,对照组采用西医常规治疗,治疗组在对照组基础上给予麻杏石甘汤加减汤治疗,治疗1个月后比较两组患者临床疗效、血气分析和肺功能改善情况。结果:治疗组显效20例,有效27例,无效3例,总有效率为94.00%;对照组显效11例,有效29例,无效10例,总有效率80.00%,两组比较,差异具有统计学意义(P<0.05)。治疗后两组患者肺功能、Pa O2、Pa CO2均有显著改善,但治疗组肺功能、Pa O2、Pa CO2改善程度均优于对照组,差异具有统计学意义(P<0.05),治疗过程中两组均未出现严重不良反应。结论:中西医结合治疗慢性阻塞性肺疾病急性加重期可显著提高临床疗效,明显改善患者血气分析指标和肺功能。

To observe the clinical effect of integrated traditional and western medicine on chronic obstructive pulmonary disease （COPD） at acute exacerbation stage. Methods： The chosen patients with COPD at acute exacerbation stage were randomly divided into treatment group and control group . The control group was treated by conventional western medicine, while the treatment group was treated with modified Maxingshigan decoction on the basis of control group. After treatment of 1 month, the clinical effects, blood gas analysis and improvement of pul- monary function of patients in two groups were compared. Results：The treatment group had 20 markedly effective cases,27 effective cases,3 ineffective cases, the total effective rate was 94.00% ; while the control group had 11 markedly effective cases ,29 effective cases, 10 ineffective cases ,the total effective rate was 80.00%. Compared two groups, the difference had statistical significance （ P 〈 0.05 ）. After treatment, the pulmonary functions, PaO2 and PaCO2 of patients in two groups were all improved significantly, but the improvement degrees of pulmonary func- tion, PaO2 and PaCO2 in treatment group were besser than in control group. The differences had statistical significance （ P 〈 0.05 ）. During the treatment, both groups had no severe adverse reactions. Conclusion ： Treating COPD at acute exacerbation stage with integrated traditional and western medicine can significantly enhance the clinical effect, significantly improve the indexes of blood gas analysis and pulmonary function of patients.