QT间期延长综合征相关药物的合理应用及防治概述

Progress of Reasonable Application and Control in Long QT Syndrome Associated with Drugs

笔者从QT间期延长综合征(long Q-T syndrome,LQTS)的临床特征、机制与影响因素、药物相关性QT间期延长综合征及临床对其防治的国内外研究进展作一综述,提出临床药师需要关注易致QT间期延长的药物使用,预防临床发生药物致急性心律失常事件等,以促进临床合理用药、提高药物的安全性。

This article has made an review including definition of drug-related long QT interval,clinical features,mechanisms and influencing factors,prevention and treatment of drug-related QT long syndrome,and its clinical research progresses. It is proposed that clinical pharmacists need to focus more attention on QT prolongation drugs. It can prevent acute arrhythmic events,and promote rationality and safety of drug.