动态动脉硬化指数与冠状动脉粥样硬化程度的相关性研究

Relationship between ambulatory arterial stiffness index and extent of coronary atherosclerosis

目的 探讨动态动脉硬化指数（AASI）与冠状动脉硬化程度的相关性.方法 对所纳入病例行冠脉CTA检查,以Gensini法评估冠状动脉粥样硬化程度,检测冠心病组患者与对照组24 h血压值,计算与比较各组间不同时段的AASI值.结果 正常对照组与冠心病组不同时段的AASI值差异均有统计学意义（P＜0.05）,且各冠脉病变组间冠脉硬化程度以及不同时段AASI差异均有统计学意义,AASI与冠脉硬化程度成正比;24 h AASI、白天AASI、夜间AASI与冠状动脉粥样硬化程度均有关,夜间AASI与冠脉粥样硬化程度相关系数最大.结论 夜间AASI与冠状动脉硬化程度的相关性最大,即夜间AASI的值越高,冠状动脉粥样硬化性程度越大.

Objective To study the relationship between ambulatory arterial stiffness index and extent of coronary atherosclerosis.Methods All subjects were underwent coronary CT angiography.Ambulatory arterial stiffness index（AASI） was measured before coronary CT angiography.AASI value between different periods in each group were calculated and compared.Results AASI between different periods in the normal control group and coronary heart disease group existed statistical difference （P 〈 0.05）.The extent of coronary sclerosis and AASI between different periods in different coronary artery lesions groups were statistically different（P 〈0.05）,AASI was proportional to the degree of coronary sclerosis,24 h AASI,DAASI,NAA SI were related to extent of coronary atherosclerosis lesions,the correlation coefficient between NAASI and extent of coronary atherosclerosis was the largest.Conclusion AASI night is related to coronary atherosclerosis most closely,namely the higher the value of the nighttime AASI,the greater the degree of coronary atherosclerosis.