窄谱红蓝光照射联合过氧化苯甲酰凝胶治疗寻常痤疮疗效观察

Effects of narrow spectrum red blue light combined with benzoyl peroxide gel in the treatment of acne vulgari

目的 观察窄谱红蓝光照射联合过氧化苯甲酰凝胶治疗寻常痤疮的疗效及不良反应.方法 对148例寻常痤疮患者采用随机、对照临床研究.患者采用简单随机法分成两组,观察组予窄谱红蓝光照射,每周2次,连续治疗12次,同时外用过氧化苯甲酰凝胶;对照组仅外用过氧化苯甲酰凝胶6周.评价疗效及安全性.结果 轻型寻常痤疮患者两组有效率分别为91.11％和69.77％,组间有效率比较,差异有统计学意义（χ2 =6.81,P＜0.05）;中重度寻常痤疮患者两组有效率分别为86.67％和58.62％,组间有效率比较,差异有统计学意义（χ2=7.23,P＜0.05）.结论 窄谱红蓝光照射联合过氧化苯甲酰凝胶治疗寻常痤疮疗效好,起效快,不良反应少.

Objective To investigate the narrow spectrum red blue light combined with benzoyl peroxide gel for the treatment of acne vulgaris and their side effects.Methods A randomized comparative clinical trial was employed.One hundred and forty-eight patients were divided into the two groups by simple random method,the observation group,2 times per week to narrow spectrum red blue light treatment of 12 times in a row,topical benzoyl peroxide gel at the same time,the control group only six weeks,topical benzoyl peroxide gel evaluate efficacy and safety.Results Two groups of efficient light acne vulgaris patients were 91.11% and 69.77% respectively,with statistically significant difference （χ2 =6.81,P 〈0.05）;Patients with moderately severe acne vulgaris effectiveness were 86.67% and 58.62% respectively,efficient comparison between groups,with statistically significant difference （χ2 =7.23,P 〈0.05）.The observation group＇s efficience was higher than the control group＇s.Conclusion Narrow spectrum red blue light combined with benzoyl peroxide gel is an effective modality for treating acne vulgaris with rapid acting and few adverse effects.