癫痫中医证素与临床特征的相关性及丹参滴丸的药效学研究

Correlation between TCM Syndrome Factors of Epilepsy and Clinical Features and the Effect of Danshen Dropping Pill

目的:探讨癫痫中医证素与临床的相关性以及丹参滴丸的药效学。方法:回顾性分析癫痫患者75例,自拟癫痫症候调查表对所选病历进行统计分析,并临床应用抗癫痫药物+丹参滴丸治疗。结果:风证与神证是癫痫的主要证素,既往史中高热惊厥后遗症、颅内感染后遗症较常见,一月数次发病频数比例较多,癫痫多发于23:00—3:00,经治疗患者的炎症因子水平下降,且氧化应激水平恢复,差异具有统计学意义。结论:风证与神证为癫痫的中医主要证素,丹参滴丸具有临床意义。

Objective：To investigate the correlation of TCM syndrome factors of epilepsy and clinical features and the pharmacodynamic of Danshen Pill. Methods ：75 cases of epilepsy patients in our hospital were selected, using self - made epi- lepsy symptom questionnaires for statistical analysis of the selected records and clinical application of anti epileptic drugs ＋ Danshen Pill treatment. Results ： The wind syndrome and spirit syndrome were the main syndromes in epilepsy, In the pasthistory of febrile seizures, intracranial infection sequelae, sequelae were common. Within one morrth, several disease fre- quency of epilepsy was multiple at 23：00 - 3：00. The level of inflammato~~ factors in the treatment of patients decreased and the level of oxidative stress recovered and the difference was statistically significant. Conclusion ：The wind syndrome and spirit syndrome are the main TCM syndrome of epilepsy and there is the clinical significance of Danshen dripping pills.