凉膈散联合西药治疗火热炽盛型口腔炎疗效及复发情况观察

Efficacy and Recurrence Western medicine of Combined with Lianggesan Fiery Flaming Type Stomatitis

目的:探讨凉膈散联合西药治疗火热炽盛型口腔炎患者疗效及复发情况。方法:68例患者根据随机数字表法随机分为观察组和对照组各34例。对照组采用西药治疗,观察组在对照组基础上结合凉膈散治疗。两组疗程均为7 d。对比分析两组疗效结束后疗效、平均起效时间和治愈时间、治疗前后中医症状积分、复发率及不良反应。结果:观察组总有效率(97.06%)显著高于对照组(76.47%),且具有统计学差异(P<0.05);观察组平均起效时间及治愈时间均显著快于对照组,且具有统计学差异(P<0.05);观察组治疗后症状积分显著低于对照组,且具有统计学差异(P<0.05);观察组复发率显著低于对照组,且具有统计学差异(P<0.05);治疗过程中两组患者均未发生明显不良反应。结论:凉膈散联合西药治疗火热炽盛型口腔炎患者疗效显著,可明显改善患者临床症状,不良反应少,且复发率低,具有重要临床研究意义。

Objective ： To investigate Lianggesan combined with Western therapy and relapse of fiery flaming type sto- matitis patients. Methods ：68 patients were randomly divided into observation group and control group according to the ran- dom number table, both 34 cases. The control group was treated with western medicine. The observation group on the basis added Lianggesan treatment. The treatment lasted 7 d. At the end, the comparative analysis of the efficacy of the two groups, an average onset time and cure time, TCM symptom score, relapse rate after treatment and adverse reactions. Re- sults ：The overall response rate （97.06%） was significantly higher （76.47%）, and there was a statistically significant difference （ P 〈 0.05） ; observation group average onset time and healing time were significantly faster than those of the control group, and there was statistically significant difference （P 〈 0.05） ; symptom scores after treatment in observation group was significantly lower than that of the control group, and there was a significant difference （P 〈 0.05 ） ; observa- tion group recurrence rate was significantly lower than that of the control group, and there was a statistically significant difference （P 〈 0.05 ）; during the treatment, the two groups had no significant adverse events. Conclusion：Combined Western Medicine and Lianggesan for fiery flaming type stomatitis patients has significant effect and can significantly im- prove the clinical symptoms with less adverse reactions and low the relapse rate. The study has important clinical signifi- cance.