中西医结合提高小儿免疫力改善反复呼吸道感染的临床研究

Combination of Chinese and Western Medicine to Improve Immunity in Children with Recurrent Respiratory Tract Infections

目的:观察口服玉屏风散合异功散治疗小儿反复呼吸道感染的临床疗效。方法:将80例符合诊断标准的反复呼吸道感染复感儿随机分为两组,每组40例,两组患者无显著差异,具有可比性。两组都给予饮食,抗生素或抗病毒等对症基础治疗,在此基础上,对照组给口服芙露饮口服液,治疗组给予口服玉屏风散合异功散进行治疗。治疗60 d,观察治疗前后两组患者的T细胞亚群,免疫球蛋白水平以及临床疗效。结果:治疗组和对照组患者的CD3+、CD4+、Ig A、Ig G、Ig M水平显著升高,CD8+水平显著降低,治疗组优于对照组;治疗组患者临床总有效率显著高于对照组。结论:使用补脾益肺法,口服玉屏风散合异功散可以提高复感儿的免疫力,治疗小儿反复呼吸道感染可以取得较好的疗效。

Objective： To observe Yupingfengsan combined Yigong San clinical efficacy in children with recurrent respiratory infections. Method： 80 patients who met the diagnostic criteria for recurrent respiratory infection complex sense of children were randomly divided into two groups,40 cases in each group. The two groups were not significantly different,comparable. 2 groups were given diet,antibiotics or anti- viral treatment and other symptomatic basis,on this basis,the control group was given oral pidotimod and treatment group received oral Yigong San and Yupingfengsan treatment. Treatment for 60 days,we observed T cell subsets,immunoglobulin levels and clinical efficacy of the two groups of patients. Result： Treatment group and the control group CD＋3,CD＋4,Ig A、Ig G、Ig M levels were significantly increased,CD8＋levels were significantly lower in the treatment group than that of the control group; overall clinical patients intreated group was significantly higher. Conclusion： Supplementing spleen and Qi method using oral Yi Gong San and Yupingfengsan together to improve children＇s complex sense of immunity and the treatment of children with recurrent respiratory tract infections can get better results.