降钙素原预测血流感染和血培养菌种分类的价值

Diagnostic utilities of procalcitonin for the prediction of bacteremia and distribution of blood culture pathogens

目的:评估PCT预测血流感染和血培养菌种的临床价值。方法:分析比较2013年1-12月间的3343例血培养结果和同时测定的PCT结果。结果:331例血流感染患者的PCT浓度显著高于2856例非血流感染者的浓度,两者的PCT中位值为3.2ng/ml对0.4ng/ml(P<0.05)。PCT鉴别两者的ROC曲线下面积(AUC)为0.86,敏感性与特异性分别为0.76和0.86.结论:PCT有助于血流感染的正确诊断和血培养污染的排除。

[ Objective ] Procalcitonin（PCT） was evaluated as a parameter for predicting bacteremia diagnosed by blood cultures. [ Methed]Blood cultures and PCT levels from 3343 specimens collected in 2013were analyzed [ Result]The PCT concentrations of bacteremia cases（ n = 331 ） were significantly higher than those of non - bacterernia（ n = 2856 ） （median： 3.2ng/ml vs 0.4ng/ ml,P 〈 0.05）. The area under the receiver operating characteristic curve （ROC - AUC） of PCT for discriminating bacteremia from non - bacteremia was 0.86, and sensivityorspecialitywas 0.76 or 0.86. [ Conclusion] PCT could be helpful in the accurate diagnosis of bacteremia.