保妇康凝胶联合诺氟沙星治疗宫颈糜烂50例疗效观察

Clinical observation of Baofukang gel combined with norfloxacin in the treatment of 50 patients with cervical erosion

目的探讨保妇康凝胶联合诺氟沙星治疗宫颈糜烂的临床效果。方法将100例宫颈糜烂患者根据随机数字表法分为观察组和对照组各50例。观察组给予保妇康凝胶和诺氟沙星联合治疗,对照组单独给予治糜灵栓治疗,比较两组患者临床症状的变化,并对临床疗效进行评价。结果观察组治愈率为86.00%,明显高于对照组的74.00%,临床症状评分改善较对照组明显,且其临床症状消失的时间短于对照组,差异均有统计学意义(P<0.05)。结论保妇康凝胶与诺氟沙星合用比治糜灵栓治疗宫颈糜烂效果更佳,且治愈时间上明显较优,值得临床上推广应用。

Objective To investigate the clinical effect of Baofukang gel combined with norfloxacin in the treatment of cervical erosion. Methods One hundred patients of cervical erosion were divided into observation group and control group according to random number table, with 50 patients in each group. The observation group was given Baofukang gel combined with norfloxacin for treatment, while the control group was only treated with Zhimiling supposi-tory. The changes of clinical symptom were compared between the two groups, and the clinical efficacy was evaluated. Results The cure rate in the observation group was significantly higher than that in the control group （86%vs 74%）. Compared with the control group, score of clinical symptoms improved in the observation group was more significant [（1.01＋0.75） vs （1.51＋0.89）], and the time for disappearance of clinical symptoms was shorter [（3＋0.41） vs （4.1＋0.15）, （16.24＋1.14） vs （23.37＋4.27）. The differences were statistically significant （P〈0.05）. Conclusion Baofukang gel com-bined with norfloxacin has better clinical effect than Zhimiling suppository in the treatment of cervical erosion, and the cure time is significantly shorter. It is worthy of clinical application.