婴幼儿腹泻乳糖不耐受与轮状病毒肠炎的关系及去乳糖饮食的疗效探讨

Investigation of the effect of infantile diarrhea and rotavirus enteritis lactose intolerance to lactose relationship between diet

目的探讨婴幼儿腹泻乳糖不耐受与轮状病毒肠炎的关系及去乳糖饮食的疗效。方法随机选取于2012年6月—2014年6月接受治疗的104例腹泻病患儿作为本次研究实验对象,根据随机数表法将患者分成观察组和对照组各52例,对患儿进行常规的抗病毒、抗腹泻治疗和补充体液保持体内水电解质的平衡,在此基础上观察组患儿采用去乳糖饮食喂养,对照组患儿则继续喂养普通奶粉或者母乳喂养,观察2组患儿治疗疗效,比较分析。结果观察组患儿治疗后41例显效,7例有效,4例无效,总有效率为92.31%;对照组患儿只有3例显效,40例无效,总有效率只有23.08%,2组比较差异有统计学意义(u=7.8504,P=0.000)。观察组患儿平均减轻体重较对照组患儿少,腹泻天数和呕吐消失时间均短于对照组患儿,2组比较差异有统计学意义(P<0.05)。结论去乳糖饮食对于治疗患儿感染轮状病毒后发生的轮状病毒肠炎和乳糖不耐受症引起的腹泻有较好疗效,且无乳糖配方奶粉安全性高,营养成分与普通配方奶粉相似,不会影响患儿正常发育,有利于婴幼儿健康成长,值得广泛推荐使用于临床实际当中。

Objective To study the effect of infantile diarrhea and rotavirus enteritis lactose intolerance to lactose rela- tionship between diet. Methods 104 cases of diarrheal disease in children from June 2012 to June 2014 to come to our hospital for treatment as subjects in this study, according to a random number table method, patients were divided into ob- servation group and control group,with 52 cases in each group,for children with conventional anti-viral,anti-diarrhea re- hydration therapy and maintain water and electrolyte balance in the body, on the basis of the observation group of children to lactose diet, the children in the control group continued feeding ordinary milk or breastfeeding, observe two groups of children therapy, comparative analysis. Results After treating, 41 cases of children with the observation group were cured ,7 cases effective, four cases ineffective, the total effective rate was 92.31% ;infants in the control group, only three cases were cured,40 cases ineffective,the total effective rate was only 23.08% ,the two groups had significant difference （ u = 7. 8504, P =0.000）. Children in observation group, the average weight loss in children was less than that of the con- trol group, the number of days of diarrhea and vomiting disappearance time were shorter than that in the control group, the difference between the two groups was statistically significant （P 〈 0.05）. Conclusion Lactose diet for rotavirus diarrhea and lactose intolerance after treatment in children with infections caused by rotavirus had a good effect, and lactose-free milk formula safety, nutrition and general formula was similar, which did not affect the normal development of children, was conducive to the healthy growth of infants and young children, it was widely recommended for use in clinical practice.