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孤独症谱系障碍病理学机制研究进展 被引量：9

Research Progress of Pathological Mechanism of autism Spectrum Disorders
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摘要 本文综述了孤独症谱系障碍可能的病理学机制,并对脑局部炎症理论、外源性因素活化ASD的易感基因及最新的治疗方法研究现状分别予以详细阐述。
作者 刘瑞芝 宋丽华 孙志刚 李素水
机构地区 河北省石家庄市精神卫生中心
出处 《中国健康心理学杂志》 2015年第5期796-799,共4页 China Journal of Health Psychology
基金 河北省科学技术研究与发展计划项目(编号:122777118)
关键词 孤独症谱系障碍 炎症 病理学 研究进展
分类号 R395.4 [医药卫生—医学心理学]
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参考文献25

  • 1Williams S C.Genetics:Searching for answers[J].Nature,2012,491:4-6.
  • 2Theoharides T C,Asadi S,Patel A B.Focal brain inflammation and autism[J].J of Neuroinflammation,2013,10:46-46.
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  • 9Galli S J,Grimbaldeston M,Tsai M.Immunomodulatory mast cells:Negative,as well as positive,regulators of immunity[J].Nat Rev Immunol,2008,8:478-486.
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二级参考文献22

  • 1Brown A C, Mehl - Madrona L. Autoimmune and gastrointestinal dys- functions:Does a subset of children with autism reveal a broader con- nection [ J ]. Expert Rev Gastroenterol Hepatol, 2011,5 (4) :465-477.
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共引文献9

同被引文献109

  • 1American Psychiatric Association. Diagnostic and statistical manual of mental disorders, fifth edition [ M ]. Arlington : American Psychiatric Publishing,2013:50 - 59.
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  • 9Pop AS, Levenga J, de Esch C, et al. Rescue of dendritic spine phenotype in Fmrl KO mice with the mGluR5 antagonist AFQO56/Mavoglurant [ J ]. Psychopharmacology, 2014,231 (6) : 1227 - 1235.
  • 10Fatemi SH, Reutiman TJ, Folsom TD, et al. GABA (A) receptor downregulation in brain of subjects with autism [J]. J Autism Dev Disord, 2009,39(2):223 -230.

引证文献9

二级引证文献47

中国健康心理学杂志
2015年 第5期

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