梅毒患者的颅脑MRI表现

MR Manifestations of Brain in Patients with Syphilis

目的探讨梅毒的颅脑MRI改变,提高对梅毒MRI表现的认识能力。方法搜集临床与血液学检查证实为梅毒患者,采用1.5 T MR进行颅脑MRI检查,分析其中5例累及颅脑的MRI表现。结果颅脑MR表现伴有多发梗死灶,大小不一,可累及皮层;T1WI呈低信号或等低混杂信号;T2WI呈高信号或等高混杂信号;T1WI增强后可有不规则强化。结论梅毒检查以实验室检查为主;MRI无特异性改变,但可以显示其病变范围,出现影像学高度怀疑的征象对早期发现及诊断该病具有重要意义。

Objective To investigate the MR manifestations of brain in patients with syphilis in order to make a further understanding of this disease. Methods The patients with clinically and hematologically proved syphilis were collected, and MR examination of the brain was performed with a 1.5T MR scanner in all patients. Abnormal changes of the brain were detected in five patients ; their MR findings were analyzed. Results On MRI, the lesions presented as multiple cere- bral infarction with different sizes, and the cerebral cortex could be involved. The lesions showed low signal or mixed low and iso-signal on T1WI, and high or mixed high and iso-signal on T2WI; the lesions showed irregular enhancement on enhanced T1 WI. Conclusion Laboratory test is the main examination method for syphilis. Syphilis has no characteristic MRI signs, but MRI can display the lesion＇ s extent. Imaging signs that are highly suspected for syphilis are very important for the early diagnosis of syphilis.