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直肠癌新辅助治疗及其相关因素对APR术后会阴部切口愈合的影响探讨 被引量:3

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摘要 经腹会阴联合切除术(abdominoperineal resection,APR),至今仍为低位直肠癌的主要手术方式,但其局部复发率远高于结肠癌[1],主要是因手术方式及解剖结构原因,局部无法达到RO切除。而随着直肠系膜全切除术(total mesorectum excision,TME)和新辅助治疗的应用,使患者DFS有了较明显的改善[2]。特别是新辅助治疗的应用,不但明显提高了手术切除率,而且使术后局部复发率也较前降低,但APR术后会阴部切口一期愈合率却较前降低,虽然近几十年在围手术期准备、手术技巧及术中预防感染等方面有了很大改进.但是APR术后会阴伤VI感染的发生率仍可达20%~47%。
作者 周青 张汝一
出处 《贵州医药》 CAS 2015年第2期139-141,共3页 Guizhou Medical Journal
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  • 1Nelson H,Petrelli N,Carlin A,et al.Guidelines 2000for colon and rectal cancer surgery[J].Natl Cancer Inst,2001,93(8):583-596.
  • 2Rullier E,Laurent C,Bretagnol F,et al.Sphincter-saving resection for all rectal carcinomas:the end of the 2-cm distal rule[J].Ann Surg,2005,241(3):465-469.
  • 3Silberfein E J,Kattepogu K M,Hu C Y,et al.Longterm survival and recurrence outcomes following surgery for distal rectal cancer[J].Ann Surg Oncol,2010,17(11):2863-2869.
  • 4Ulrich A,Weitz J,Slodczyk M,et al.Neoadjuvant treatment does not influence perioperative outcome in rectal cancer surgery[J].Int J Radiat Oncol Biol Phys,2009,75(1):129-136.
  • 5Gruessner U,Clemens M,Pahlplatz PV,et al.Improvement of perineal wound healing by local administration of gentamicin-impregnated collagen fleeces after abdominoperineal excision of rectal cancer[J].Am J Surg,2001,182(5):502-509.
  • 6DE Bruin AF,Gosselink MP,Wijffels NA,et al.Local gentamicin reduces perineal wound infection after radiotherapy and abdominoperineal resection[J].Tech Coloproctol,2008,12(4):303-307.
  • 7Artioukh DY,Smiyh RA,Gokul K.Risk factors for impaired healing of the perineal wound after abdominoperineal resection of rectum for carcinoma[J].Colorectal Dis,2007,9(4):362-367.
  • 8Chadwick MA,Vieten D,Pettitt E,et al.Short course preoperative radiotherapy is the single most important risk factor for perineal wound complications after abdominoperineal excision of the rectum[J].Colorectal Dis,2006,8(9):756-761.
  • 9Gerard JP,Conroy T,Bonnetain F,et al.Preoperative radiotherapy with or without concurrent fluorouracil an41eucovorin in T3-4rectal cancers:results of FFCD 9203[J].J Clin Oncol,2006,24(28):4620-4625.
  • 10PapaconstantinOu HT,Bullard KM,Rothenberger DA,et al.Salvage abdominoperineal resection after failed Nigro protocal:modest Success,major morbidity[J].Colorectal Dis,2006,8(2):124-129.

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