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孕激素膜受体1在40例卵巢癌中的表达及意义 被引量：2

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摘要 近年来发现孕激素膜受体1（PGRMC1）是一种新型膜激素受体,广泛存在于细胞膜、微粒体及突触膜上。PGRMC1是作为一种接头蛋白并参与细胞信号转导通路,与肿瘤细胞增殖,侵袭密切相关。PGRMC1在乳腺癌、结肠癌、卵巢癌和肺癌等多种肿瘤细胞和肿瘤组织系中高表达,表明PGRMC1促进肿瘤的生存和发展。目前关于PGRMC1在卵巢癌发生、发展过程中作用少有报道,
作者 任峻青 郑洪
机构地区 遵义医学院附属医院病理科
出处 《贵州医药》 CAS 2015年第4期308-309,共2页 Guizhou Medical Journal
基金 贵州省自然科学基金[黔科合J字(2007)2128号]
关键词 孕激素膜受体1 卵巢癌
分类号 R737.31 [医药卫生—肿瘤]
  • 相关文献

参考文献4

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二级参考文献12

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共引文献9

同被引文献22

  • 1胡军,曹建初,钟愉.乳腺癌雌孕激素受体和C-erbB-2的表达及意义[J].贵州医药,2004,28(9):849-850. 被引量：1
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  • 6Du SP,Guo ZY,Chen BB,et al.Electrochemiluminescence immunosensor for tumor markers based on biological barcode mode with conductive nanospheres[J].Biosensors&Bioelectronics,2014,53(9):135-141.
  • 7Mortazavi SJ,Mozdarani H.PSA,CA19-9 and CEA tumor markers in blood serum of inhabitants of Ramsar,Iran,Heidary et al.,Journal of Environmental Radioactivity[J].J Environ Radioact,2014,132:121-122.
  • 8Jia XL,Liu N,Ma ZF,et al.A label-free immunosensor based on graphene nanocomposites for simultaneous multiplexed electrochemical determination of tumor markers[J].Biosensors&Bioelectronics,2014,53c(4):160-166.
  • 9Avisnata D,Kunkel M,Joudeh J,et al.Clinico-pathological correlation of serial measurement of circulating tumor cells in 24metastatic colorectal cancer patients receiving chemotherapy reveals interpatient heterogeneity correlated with CEA levels but independent of KRAS and BRAF mutation[J].Cancer Biology Therapy,2015,16(5):709-713.
  • 10Gao J,Guo ZK,Su FJ,et al.Ultrasensitive electrochemical immunoassay for CEA through host-guest interaction of beta-cyclodextrin functionalized graphene and Cu@Ag core-shell nanoparticles with adamantine-modified antibody[J].Biosensors&Bioelectronics,2015,63C:465-471.

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二级引证文献22

贵州医药
2015年 第4期

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