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肠促胰素对1型糖尿病患者血糖及胰岛功能的影响

Effects of incretin on blood glucose and islet function in type 1 diabetic patients
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摘要 肠促胰素类药物因其葡萄糖依赖性的降糖作用及对胰岛细胞的保护作用受到广泛关注.近年研究发现,肠促胰素类药物不仅可降低1型糖尿病患者的血糖,改善血糖波动,还可以改善患者胰岛功能,减少氧化应激对胰岛细胞的损害,从而有助于患者的整体血糖的控制,延缓并发症的发生. Incretin has obtained more and more attention because of its glucose-dependent blood glucose lowering effects and its islet protection.Recently it is found that incretin-based drugs can lower blood glucose and improve blood glucose fluctuation in patients with type 1 diabetes.It can also improve islet function,and reduce the damage of oxidative stress to islet cells,which are helpful for the long term control of blood glucose and the delay of diabetic complications.
出处 《国际内分泌代谢杂志》 2015年第3期196-198,共3页 International Journal of Endocrinology and Metabolism
基金 南京市第三批科技发展计划项目(201303005)
关键词 GLP-1类似物 DPP-4抑制剂 1型糖尿病 血糖 胰岛功能 GLP-1 analogues DPP-4 inhibitors Type 1 diabetes mellitus Blood glucose Islet cell function
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参考文献27

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