创伤性颅脑损伤发展为进展性出血性脑损伤的研究进展

The research progress of traumatic craniocerebral injury development for progressive hemorrhage intracranial

创伤性颅脑损伤易发生凝血功能异常,而后发生的进展性出血性脑损伤与脑损伤患者的预后有密切联系,进展性出血性脑损伤的发病机制较为复杂,主要包括组织因子释放、纤溶系统亢进、血小板作用、C反应蛋白通路、血液稀释作用、炎性反应、代谢性酸中毒、低体温等几个方面,本研究就创伤性颅脑损伤后发生进展性出血性脑损伤的发展机制作一综述。

Traumatic craniocerebral injury prones to coagulant function abnormality,and then the progress of hemor-rhagic brain injury is closely related to the prognosis of patients with brain injury,the progress of the pathogenesis of hemorrhagic brain injury is relatively complex,mainly including tissue factor release,fibrinolytic system goes,platelet function,C-reactive protein,blood dilution effect,inflammation,metabolic acidosis,hypothermia,this paper has reviewed the development mechanism of hemorrhagic brain injury occured after traumatic brain injury.