双水平无创正压通气在慢性阻塞性肺疾病伴重度呼吸衰竭中的应用

Application of Bi-level Noninvasive Positive Pressure Ventilation in Patients of Chronic Obstructive Pulmonary Disease with Severe Respiratory Failure

目的:进一步研究并探讨双水平无创正压通气在慢性阻塞性肺疾病伴重度呼吸衰竭患者中的临床应用效果。方法:选取2012年12月-2014年6月于笔者所在医院治疗的136例慢性阻塞性肺疾病伴重度呼吸衰竭患者为研究对象,分为对照组和研究组,各68例,研究组在对照组常规治疗基础上加用双水平无创正压通气,对两组患者的各项临床疗效指标进行分析。结果:(1)研究组患者治疗前后p H值、Pa O2、Pa CO2等三项指标的改善均优于对照组(P<0.05);(2)研究组患者死亡率低于对照组(P<0.05);(3)与对照组相比,研究组患者平均住院时间明显缩短(P<0.05)。结论:对于慢性阻塞性肺疾病伴重度呼吸衰竭的患者在常规治疗的基础上加用双水平无创正压通气可明显改善临床疗效,值得推荐。

Objectiye： To further study and discuss the clinical effect of bi-level noninvasive positive pressure ventilation in patients of chronic obstructive pulmonary disease with severe respiratory failure.Method： 136 patients chronic obstructive pulmonary disease with severe respiratory failure from December 2012 to June 2014 in our hospital for treatment were chosen as the research objects, they were divided into the study group and the control group, 68 cases in each group.Compared with the control group, the study group on the basis of conventional treatment combined with bi-level noninvasive positive pressure ventilation. The clinical treatment effects of two groups were compared.Result： （1）The pH value, PaO2, PaCO2 three indicators of the study group were better than those of the control group（P〈0.05）.（2）The incidence of death of the study group was lower than that of the control group（P〈0.05）.（3）The average length of stay of the study group was lower than that of the control group（P〈0.05）.Concluslon： For patients with severe respiratory failure with chronic obstructive pulmonary disease on the basis of conventional treatment combined with bi-level noninvasive positive pressure ventilation can obviously improve the clinical effect.